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Instruments designed to measure and/or control the flow of test liquids and gases. Products include process flow computers, flow measurement controllers, and process flowmeters and may be able to record flow data digitally.
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Also available in 1mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor. purity: 98%
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ARS-1323 is a KRAS G12C inhibitor that specifically binds to the cysteine residue on the mutant K-Ras protein, locking it in the GDP-bound conformation. This action blocks K-Ras activation and downstream signaling pathways. It can be used to investigate signal transduction mechanisms and growth characteristics of tumor cells driven by K-Ras G12C.
Targets Ras
Inhibits GPCR/G Protein and MAPK/ERK pathway
Powder storage: -20°C for 3 years, 4°C for 2 years
In solvent storage: -80°C for 2 years, -20°C for 1 year
Solubility in DMSO: 100 mg/mL (232.10 mM)
In vivo solubility options available
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Aluminum is economical and good for general use with noncorrosive gases and liquids. Brass is economical and good for use with water. Stainless steel withstands higher temperature and pressure and features excellent chemical compatibility. Valved meters have valves mounted at the bottom/inlet, typically used for positive pressure with liquids and gases. The valve can be reconfigured to mount at the top/outlet, often for vacuum applications. All correlated flowmeters come with data sheets for water and air at standard temperature and pressure (STP).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
The substitution of metal fittings with PTFE eliminates a potential contamination source for high-purity applications. The glass tube utilizes a fused ceramic scale for a precise, permanent measuring guide. In addition, a vertical-tangential locator line provides readings with hairline accuracy. Further improving readability is a front shield that magnifies the scale 16%. An anodized aluminum frame protects the heavy-walled glass flowtube; a white acrylic backplate protects and enhances viewing in the protective frame. Select a flowmeter with a valve for flow rate control. The standard valve is suitable where high resolution metering is not essential. The high precision valve features a fine-adjust 16-turn "non-rising stem" to more accurately set your desired flow rate. All flowmeters come with correlation data sheets for water and numerous gases (listed below) at standard temperature and pressure (STP).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
This full range of direct-reading flowmeters provide a robust solution for your laboratory that eliminates the need for reading conversions. Valved flowmeters have a valve mounted at the inlet (bottom) of the flowmeter. This arrangement is typically used for positive pressure applications for liquids and gases. The valve can be reconfigured to mount at the outlet (top), often for vacuum applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More